Dr SREEKANTH R
MSc, PhD
ASSOCIATE PROFESSOR
Articles in Journals
Sl.No. Title Name of Journal / Vol. No. / Issue No. / Page Nos ISSN No. Date Published
1 Discovery of tetrahydro γ-carboline based novel glucose uptake agent for the treatment of diabetes and Alzheimer?s diseases Results in Chemistry / 11 / / - 0223-5234 01-Oct-2024
2 Covalent ligands of Nuclear Receptors European Journal of Medicinal Chemistry / 261 / / - 0223-5234 05-Dec-2023
3 Structural insights into Plasmodium PPIases Frontiers in Cellular and Infection Microbiology / 12 / / - 2235-2988 02-Sep-2022
4 Prostaglandin A2 interacts with Nurr1 and ameliorates behavioral deficits in Parkinson?s disease fly model NeuroMolecular Medicine / 24 / / - 1535-1084 28-Apr-2022
5 Antiviral activity against Middle East Respiratory Syndrome Coronavirus by Montelukast, an anti-asthma drug Antiviral Research / / / - 0166-3542 01-Jan-2021
6 PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function Nature Chemical Biology / 16 / / - 1552-4450 25-May-2020
7 Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog Protein Science / 28 / / - 0961-8368 01-Mar-2019
8 Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface Scientific Reports / 8 / / - 2045-2322 26-Mar-2018
9 Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa Journal of Bacteriology / 200 / / - 0021-9193 12-Jan-2018
10 Structural and mechanistic insights into nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin Nucleic Acids Research / 44 / / - 0305-1048 07-Apr-2016
11 Crystal structure of the FK506 binding domain (FKBD) of human FKBP25 in complex with FK506 Protein Science / 25 / / - 0961-8368 08-Jan-2016
12 Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease Proceedings of the National Academy of Sciences (USA) / 112 / / - 0027-8424 29-Jun-2015
13 Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport Scientific Reports / 5 / / - 2045-2322 29-May-2015
14 BH3 induced conformational changes in Bcl-XL revealed by crystal structure and comparative analysis Proteins: Structure, Function and Bioinformatics / / / - 1097-0134 01-Jul-2015
15 Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity Proteins: Structure, Function and Bioinformatics / 82 / / - 1097-0134 05-Jul-2014
16 Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35 ACS Medicinal Chemistry Letters / / / - 1948-5875 16-Sep-2013
17 C-HO hydrogen bonds in FK506-binding protein-ligand interactions Journal of Molecular Recognition / 26 / / - 0952-3499 01-Oct-2013
18 Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent Scientific Reports / / / - 2045-2322 26-Aug-2013
19 Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax Eukaryotic Cell / / / - 1535-9786 22-Feb-2013
20 The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization Journal of Biological Chemistry / / / - 0021-9258 23-Jan-2013
21 High-resolution crystal structure of FKBP12 from Aedes aegypti Protein Science / / / - 0961-8368 19-Apr-2014
22 Oligomerization propensity and flexibility of yeast frataxin studied by X-ray crystallography and small-angle X-ray scattering Journal of Molecular Biology / / / - 0022-2836 16-Dec-2011
23 Bacterial ferrochelatase turns human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase Journal of Biological Inorganic Chemistry / / / - 0949-8257 01-Feb-2011
24 Metal induced structural changes observed in hexameric insulin International Journal of Biological Macromolecules / / / - 0141-8130 01-Jan-2009
25 Characterization of alpha helices interacting with nucleic acids Computational Biology and Chemistry / / / - 1476-9271 01-Oct-2008
26 Molecular basis of chromium insulin interactions Biochemical Biophysical Research Communications / / / - 1476-9271 02-May-2008
27 Structural Interpretation of reduced insulin activity as seen in the crystal structure of human Arg-insulin Biochimie / / / - 0300-9084 01-Mar-2008
28 The study of helical distortions due to environmental changes: Choice of parameters, Biophysical Chemistry / / / - 0301-4622 01-Jan-2007
Participation in Seminars/Conferences/Symposium
Sl.No. Name of the Conference /Seminar /Symposium Type of Program Title of the Article Role Venue/Place Date
1 A research mini symposium on Informatics and Omics SYMPOSIUM A research mini symposium on Informatics and Omics PARTICIPANT) IBAB (Institute of Bioinform. and Appl. Biotech.)BENGALURU 06/12/2025
2 Symposium on Emerging Trends in Agricultural Entrprenership SYMPOSIUM Symposium on Emerging Trends in Agricultural Entrprenership PARTICIPANT) CHRIST (Deemed to be University) 10/12/2025
MPhil/PhD Guided/Adjudicated
Sl.No. Title Name of Student Institution Role Status Month Year
1 Chromatographic techniques for the purification of Monoclonal antibodies (mAbs) SONIT KUMARI Christ University SUPERVISOR Ongoing July 2021
Research Project
Sl.No. Name of the Research Project Investigator(s) Sponsors Internal/External
1 Targeting Nuclear Receptors and Kinases Internal
Workshop/FDP/Training programme
Sl.No. Name of the Workshop/FDP/Training programme Name of Organiser Level Role Date
1 Advancement in Life Sciences Research Department of Life Sciences, CHRIST (Deemed to be University),  Participant 29/09/2025
2 Faculty Development Program 2025 CHRIST (Deemed to be University),  Institutional Participant 19/05/2025
3 Learner-Centered Andragogy CHRIST (Deemed to be University),  Participant 24/03/2025